In this issue...

Office of Research News...

Excellence in Research Awards

New Funding Opportunities

Pre-filled Application Packages (pdf)

Proposal Submission Policy

IACUC news

IRB Update

Biological Safety

Fast Facts

NIH News

Loan Repayment Programs

NIH Funding opportunities

Extramural Nexus

RePORTER Tool

Research news

Research Matters

The Research Support Newsletter


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Upcoming Events

Mark your calendars!

The office of Research
cordially invites the UMMC community to

The Excellence in Research Awards Ceremony and Reception

to honor faculty who have distinguished themselves with exceptional research

WHO: All interested faculty, staff and students
WHEN: Wed., October 28, 2009,11:30 a.m.
WHERE: Norman C. Nelson Student Union

Parking is available in the Visitor Parking lot D (across from the School of Dentistry or behind the Student Union)
For more info, call Janet Keniston at 5-5000


The Office of Research is hosting the webinar:

'Interpretation & Implementation of NSF's Requirement to facilitate the Ethical Conduct of Research'

This webinar will provide an overview of NSF's new requirement for institutions receiving NSF funds to provide tranining and oversight in the responsible and ethical conduct of research

WHO: All NSF applicants, interested faculty & research staff
WHEN: Thursday, November 19, 2009,12:00-1:30 p.m..
WHERE: Location to be determined

Please RSVP your attendance to Sondra Floyd in the Office of Research by Monday, November 2, 2009.

Read more.......


The office of Research invites you to attend

'A Hands-on traning in completing NIH Adobe grant application packages'

This one-hour training will lead you through each section of the application and more....

WHO: All faculty, staff & students
WHEN: Wednesday, November 11, 2009,
1:00-2:00 p.m..

WHERE: CW 209, Classroom Wing computer lab
**RSVP required since seating is limited**
Please RSVP your attendance to Janet Keniston ASAP


 


 

Kudos!

Congratulations to Research Awardees for fiscal year 2010
July-September

Federal Research Awardees by Department:
Principal Investigator Project Title Sponsor
Anatomy:
Dr. Paul May Midbrain Circuitry for Neuronal Control of Gaze National Eye Institute
Biochemistry:
Dr. Victor Davidson Structure Function & Biosynthesis of Respiratory Enzymes National Institute of General Medical Sciences
Dr. Michael Hebert Nuclear bodies and ribonucleoprotein biogenesis - Recovery Act supplement National Institute of General Medical Sciences
Dr. Drazen Raucher Targeted Delivery of Therapeutic Peptides by Genetically Engineered Biopolymers National Science Foundation
Dr. Donald Sittman Mississippi Functional Genomics Network University of Southern Mississippi/NIH
Cancer Institute:
Dr. Lucio Miele PKC Alpha as a marker for Logical Therapeutic Approaches to Breast Cancer University of Illinois at Chicago
Emergency Medicine:
Dr. Richard Summers Digital Astronaut Project: Integrative Computer Model for the Analysis of Human Physiology in Microgravity NASA - Johnson Space Center
Medicine:    
Dr. Thomas Abell Establishing UMMC's Clinical Center in NIDDK's Gastroparesis Research Consortium National Institute of Diabetes, Digestive and Kidney Diseases
Dr. Luis Juncos Suppressor ANGII Determines Acute & Chronic Renal Injury - Recovery Act Supplement National Institute of Diabetes, Digestive and Kidney Diseases
Dr. Deborah Konkle-Parker Multi-dimensional HIV Adherence Intervention National Institute of Mental Health
Dr. Mario Sims Disparities in CHD in the Jackson Heart Study National Heart, Lung and Blood Institute
Dr. Herman Taylor Diabetes and Insulin Resistance Effect on Echo LV Structure and Function-Minority Supplement National Heart, Lung and Blood Institute
Dr. Herman Taylor Jackson Heart Study - Examination Center National Heart, Lung and Blood Institute
Microbiology:
Dr. Eva Bengten The identification and characterization of virus specific cytotoxic cells in channel catfish U.S. Department of Agriculture
Dr. Richard O'Callaghan Staph Keratitis: Mechanism and Arrest of Ocular Damage National Eye Institute
Dr. David Robinson Horizontal Genetic Transfer in Staphylococi National Institute of General Medical Sciences
Otolaryngology & Communicative Sciences:
Dr. Wu Zhou Supplement (EQ) for Multiplicative Computation in the Vestibulo-Ocular Reflexes - Recovery Act Supplement National Institute on Deafness and Other Communicatin Disorders
Pediatrics:
Dr. Rathi Iyer Additional Centers for the Sickle Cell Disease Clinical Research Network New England Research Institutes//NHLBI
Pharmacology & Toxicology:
Dr. George Booz Regulation of IL-6 Type Cytokine Cardioprotective Signaling in the Ischemic Heart National heart, Lung and Blood Institute
Dr. George Booz Regulation of IL-6 Type Cytokine Cardioprotective Signaling in the Ischemic Heart - Recovery Act Supplement National heart, Lung and Blood Institute
Dr. Roy Duhe Pathophysiological Redox Regulation of JAK2 in Diabetes - Recovery Act funded National Institute of Diabetes and Digestive and Kidney Diseases
Physiology & Biophysics:
Dr. Barbara Alexander Research Infrastructure in Minority Institutions: Strengthening Biomedical Research Tougaloo College/NIH
Dr. Robert Hester Innovations through Computational Sciences-EPSCOR Proposal Mississippi State University/NSF
Dr. Ruisheng Liu Regulation of Superoxice Production at the Macula Densa During TGF National Heart, Lung and Blood Institute
Dr. Ruisheng Liu Regulation of Superoxide Production by the Macula Densa during TGF - Recovery Act Supplement National Heart, Lung and Blood Institute
Dr. Christine Maric Estrogen and Inflammation in Diabetic Nephropathy National Institute of Diabetes, Digestive and Kidney Diseases
Dr. Michael Ryan Blood Pressure, Renal Hemodynamics, and Inflammation Recovery Act Supplement National Institute of Diabetes, Digestive and Kidney Diseases
Dr. David Stec The Renal Medulla and Hypertension-Recovery Act supplement National Heart, Lung and Blood Institute
Dr. David Stec The Renal Medulla and Hypertension National Heart, Lung and Blood Institute
Psychiatry & Human Behavior:
Dr. Scott Coffey Affect Regulation Training Alcoholics National Institute on Alcohol Abuse and Alcoholism
Dr. Kim Gratz Developing an emotion regulation group therapy for self-harm among women with BPD National Institute of Mental Health
Dr. Craig Stockmeier Center for Research Excellence in Psychiatric Neuroscience National Center for Research Resources
Dr. Grazyna Rajkowska Cortical Cell Pathology in Depression Duke University/NIMH
Dr. Julie Schumacher Program of Excellence in Training and Dissemination of Motivational Interviewing Natinal Institute on Drug Abuse
Dr. William L Woolverton Self-administration of drug combinations: Polydrug abuse National Institute on Drug Abuse
Non-Federal Research Awardees by Department :
***This is a list of awardees from Non-profit, Voluntary Health organizations etc.,***
Medicine:
Dr. Michael Flessner Implanted Biomaterials, Local Inflammation, and the Heart American Heart Association
Neurosurgery:
Dr. Eddie Perkins Thermally Targeted Delivery of Therapeutic peptides Thermally Targeted Therpeutics/NCI
Opthalmology:

Dr. Ching Chen

Epidemiology and Genetics of Diabetic Retinopathy in the Jackson Heart Study

Friends of Massachusetts Eye and Ear Infirmary
Orthopedic Surgery:
Dr. Matt Futvoye Vacuum Assisted Closure of Acetabular Fracture incisional Wounds in the Obese Orthopedic Trauma Association
Pediatrics:
Dr. Gail Megason Children's Oncology Group National Childhood Cancer Foundation
Physiology & Biophysics:
Dr. Alexandre DaSilva Antidiabetic and Cardiovascular Actions of Leptin Mediated by the Central Nervous System American Heart Association
Dr. Shereen Hamza Obesity hypertension: differential central modulation of appetite, metabolism and cardiovascular homeostasis by leptin (Post-doctoral fellowship) Alberta Heritage Foundation
Dr. Birdie Lamarca The Role Agonistic Autoantibodies to the Angiotensin II Type I Receptor in Mediating Hypertension During Pregnancy American Heart Association
Dr. Shankar Munusamy Mechanisms of Obesity-induced Renal Injury American Heart Association
Sydney Murphy Pregnancy, the kidney, and hypertension American Heart Association
Joshua Speed Endothelin, the Kidney & Hypertension American Heart Association
Marcia Venegas-Pont Protective role for PPAR gamma in hypertension associated with systemic lupus American Heart Association

****This is a list of research awardees for the first quarter of FY'2010. We apologize if any one's name has been inadvertently left out of this list. Please let us know and we will capture the information in the next issue of the Waves.****


Loan repayment Programs from NIH:

You do the research. NIH will repay your student loans. That is the idea behind the National Institutes of Health Loan Repayment Programs (LRPs).

THE FY 2010 APPLICATION CYCLE IS OPEN!
The Extramural New and Renewal Deadline is December 1, 2009 at 8 PM EST

NIH wants to encourage outstanding health professionals to pursue careers in biomedical, behavioral, social, and clinical research. If you commit at least two years to conducting qualified research funded by a domestic nonprofit organization or U.S. federal, state, or local government entity, NIH may repay up to $35,000 of your qualified student loan debt per year, including most undergraduate, graduate, and medical school loans. Loan repayment benefits are in addition to the institutional salary you receive for your research. Please visit http://www.lrp.nih.gov/ for more details about how to apply for this program.


New Funding Opportunities:

National Science Foundation (Office of Integrative Activities (OIA) will solicit applications for the Major Research Instrumentation Program for the January 28, 2010 deadline.
Because the MRIP is a limited competition, this program requires UMMC to screen the applications and allow only the number permitted by the sponsor to be submitted for funding consideration.

If you are interested in applying for the opportunity above, notify Pam Tazik ptazik@dor.umsmed.edu in the Office of Research by Monday, November 2, 2009.

UMMC's limited submission competition guidelines are available at http://dor.umc.edu/RT/policies/Limited_Submission_ Competition_ GuidelinesFinal.pdf


The Bill & Melinda Gates Foundation is now accepting grant proposals for the Grand Challenges Explorations, a $100 million initiative to encourage bold and unconventional global health solutions.

Anyone can apply, regardless of your prior experience or institutional affiliation. Previous winners include graduate students, entrepreneurs at start-up companies, and creative thinkers from all fields of research. Proposals are currently being accepted online until November 2, 2009 on the following topics:

Click here to apply now.

Initial grants will be $100,000 each, and projects showing promise will have the opportunity to receive additional funding of up to $1 million. Full descriptions of topics and application instructions are available at: http://www.grandchallenges.org/explorations


UMMC American Cancer Society-Institutional Research Grant Program:

This is a final call for applications for individual ACS-IRG awards under the
UMMC-American Cancer Society Institutional Research Grant Program. These awards are typically up to $25,000 ($50,000 maximum for extraordinary applications) and are available to full-time faculty of the UMMC, as well as to faculty with joint UMMC/VA appointments, at the Instructor or Assistant Professor rank. Click here for eligibility requirements and details.

Applications are due to the Committee by Tuesday, December 1, 2009.
Applications must be routed through the UMMC Office of Research with an accompanying completed transmittal form, in accordance with the Policy on Routing and Approval of Intramural Research Proposals.
All compliance certifications must be verified before funds can be disbursed, and all funds must be disbursed before December 31, 2009. For further questions, please contact
Dr. Roy Duhe, Professor of Pharmacology and Toxicology at 601-984-1625 or email to rduhe@pharmacology.umsmed.edu




Recovery Act Limited Competition: Building Sustainable Community-Linked Infrastructure to Enable Health Science Research (RC4)


The NIH has established a new program entitled 'Building Sustainable Community-Linked Infrastructure to Enable Health Science Research', hereafter called the 'Community Infrastructure' grants program'. This NIH Funding Opportunity Announcement (FOA), supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009, Public Law 111-5, solicits applications from domestic (United States) institutions/organizations proposing to support the development, expansion, or reconfiguration of infrastructures needed to facilitate collaboration between academic health centers and community-based organizations for health science research. Earliest application date is November 11, 2009 and applications are due by December 11, 2009.

The Recovery Act Limited Competition: Building Sustainable Community-Linked Infrastructure to Enable Health Sciece Research (RC4)

This NIH Funding Opportunity Announcement (FOA), supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009, Public Law 111-5, solicits applications from domestic (United States) institutions/organizations proposing to support the development, expansion, or reconfiguration of infrastructures needed to facilitate collaboration between academic health centers and community-based organizations for health science research. Such collaboration should transform the way in which health science research is conducted in communities, and accelerate the pace, productivity, dissemination, and implementation of health research; applications that build upon extant collaborative infrastructures supported by other Federal agencies are strongly encouraged. Here is the link to the full announcement : http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-010.html


Pre-filled parent application packages with institutional information for the R01, R03 and R21 mechanisms are available on our website now. You need to have a compatible version of Adobe Reader - 8.1.3 or higher to open these packages. If you need further assistance, please call the office of Research at 601-815-5000.


Reminder - Grant submission policy:

Final and complete grant application packages are due in the Office of Research
5 business days prior to the sponsor submission deadline.  These packages must be accompanied by a completed transmittal form with the PI's and Chair/Dean's signatures.  Packages that arrive with less than the 5 day turnaround, are incomplete, do not have final attachments, or do not have a transmittal form  will be handled on a first come first served basis. More on submission policy details.


Biological safety Update :

Shipping Infectious Substances and Dry Ice
:

It's the Law! Federal regulations require that all persons involved in the transportation of hazardous materials be trained. The purpose is to increase employees' safety awareness and be an essential element in reducing transportation incidents.
Department of Environmental Health and Safety provides Shipping Infectious Substance and Dry Ice training and encourages investigators to have a designated person from their lab to be properly trained. For more information, please contact Yolanda Griffin, Biological Safety Officer at 601-815-5074 or via email at vgriffin@hr.umsmed.edu.

Please visit the IBC website for guidelines and policies for activities involving bio-hazardous materials and/or Recombinant DNA. It is the primary responsibility of investigators to (1) Determine whether or not activities under their direction involve recombinant DNA or microbiological biohazards. (2) Classify the biohazard risk group and determine the biosafety level at which the activity should be conducted. (3) Register the activity with and seek approval from the UMC Institutional Biosafety Committee (IBC). (4) Comply with federal and institutional guidelines for safe handling of biohazard materials. (5) Inform personnel of risk potential and provide them with adequate training to minimize their exposure.


IACUC News:

Protocol Submission:

Beginning January 1, 2010, investigators will be required to use the revised Animal Activity Protocol Form (rev. 10/2009) that was recently approved by the IACUC and now posted for use on the IACUC website: http://iacuc.umc.edu/iacucforms.html. The format of the Assurance/Search/Narrative section has been changed to assist investigators in providing the necessary information required by the USDA and OLAW regulations. The Roland Medical Library reference desk (ext. 4-1231) is available to provide additional assistance with protocol searches, if needed.

IACUC Educational Seminar:

Diversion Investigator Angela Lee's October 14th PowerPoint presentation is now available on-line and can be found on the IACUC website at http://iacuc.umc.edu/ -The 'nuts and bolts' on the DEA License Application Process and 'Appropriate Disposal of Expired Controlled Substances'

Investigator Lee advised that in the upcoming year, the Drug EnforcementAgency will resume inspection of Research laboratories at the University of Mississippi Medical Center. If you are the holder of a DEA license, are your records and security of drugs on hand in order? Investigators are encouraged to check out the PowerPoint presentation, ask questions and take necessary action to be compliant or maintain compliance with the DEA Regulations.

IACUCPolicy Review:
Management of Suspected Protocol Noncompliance


At the request of the Research Compliance Subcommittee the IACUC has now provided examples of 'Animal Research Related Issues of Noncompliance' with its policy now found on the IACUC website at the following link:
http://iacuc.umc.edu/documents/ManageSuspectedProtNoncompl_000.pdf

The IACUC recognizes that over the life of an Animal Activity Protocol, the experimental studies with animals may 'drift' or take seemingly minor departures from their original documented plan.These deviations from the original, IACUC-approved protocol are considered issues of noncompliance if they have not been previously covered by an amendment to the original protocol.

All Principal Investigators and their staff are requested to review and become familiar with the IACUC policy that governs how instances of noncompliance are addressed by the IACUC. What may seem 'small' in the midst of a procedure may have 'large' consequences after the fact, if not already approved in the Animal Activity Protocol. If a study action is happening to the live animal, there should be a description of the action in the approved Animal Activity Protocol or a subsequent amendment.


IRB Update:
IRB Policy Review: Management of Suspected Noncompliance

At the request of the Research Compliance Subcommittee, the IRB has created a 'fast fact' sheet with some examples of major violations of human research noncompliance. This information can be found in the Guidance section on the IRB website, http://irb.umc.edu/guidance.html

All Principal Investigators and their staff should review and become familiar with IRB policies, including those that explain how instances of suspected noncompliance are addressed. What may seem minor may have "large" consequences if it was not reviewed and approved by the IRB prior to implementation. More detailed information and all of the IRB policies and Procedures can be found at http://irb.umc.edu/newdoc/P&P_05-v3.2.pdf.

Reminder: IRB Review of Research Applications/Proposals:
UMMC is required to review all applications and proposals submitted for human subject research and to verify that the research described matches the corresponding protocol submitted to the IRB. A copy of the application or proposal should be submitted to the IRB as a part of the Initial Application, along with the protocol to be reviewed. The IRB will verify that the research described in the application or proposal is consistent with any corresponding protocol(s) submitted to the IRB and a copy of the application or proposal will be retained as a part of the IRB study file. No funds will be distributed until the verification has been made and the protocol has received IRB approval.


RePORTER - Research Portfolio Online Reporting Tool Expenditures and Results Tool -

On September 1, 2009, the CRISP system will be retired and replaced by the NIH RePORTER.

The NIH has released to the public a beta version of its new Research Portfolio Online Reporting Tool Expenditures and Results (RePORTER) tool.

http://projectreporter.nih.gov/reporter_SearchResults.cfm

You can get the listing of various awards by fiscal year, State and organization by leaving all other search fields as default all. These lists can also be downloaded to Excel.

RePORTER also provides links to PubMed Central, PubMed, and the US Patent & Trademark Office Patent Full Text and Image Database for more information on research results. New features will be added to RePORTER in several releases throughout fiscal year 2010.